Reproducibility of tissue autofluorescence for screening potentially malignant disorders

Screening for oral potentially malignant disorders among areca (betel) nut chewers in Guam and Saipan

BACKGROUND The Mariana Islands, including Guam and Saipan, are home to many ethnic subpopulations of Micronesia. Oral cancer incidence rates vary among subpopulations, and areca (betel) nut chewing, a habit with carcinogenic risks, is common. Our objectives were to conduct a screening program to detect oral potentially malignant disorders (OPMD) in betel nut chewers, measure their betel nut che...

Oral Cancer and Oral Potentially Malignant Disorders

Oral potentially malignant disorders: Is malignant transformation predictable and preventable?

Leukoplakia is the most common potentially malignant disorder of the oral mucosa. The prevalence is approximately 1% while the annual malignant transformation ranges from 2% to 3%. At present, there are no reliable clinicopathological or molecular predicting factors of malignant transformation that can be used in an individual patient and such event can not truly be prevented. Furthermore, foll...

efficacy of diode laser for the management of potentially malignant disorders

introduction: laser dentistry is a one of the upcoming advanced treatment modality for oral mucosal lesions. diode laser is a soft tissue laser that has found much acceptance in all branches of dentistry. available compact size and feasibility has render diode laser an enhanced tool for today’s clinical practice. the aim of this study is to determine the efficacy and safety of diode laser for t...

Risk Stratification of Oral Potentially Malignant Disorders in Fanconi Anemia Patients Using Autofluorescence Imaging and Cytology-On-A Chip Assay12

Fanconi anemia (FA) is a hereditary genomic instability disorder with a predisposition to leukemia and oral squamous cell carcinomas (OSCCs). Hematopoietic stem cell transplantation (HSCT) facilitates cure of bone marrow failure and leukemia and thus extends life expectancy in FA patients; however, survival of hematologic malignancies increases the risk of OSCC in these patients. We developed a...